~5h 35mTotal estimate
~€105–400Rough fare per person
Flight to Medellín
Panama City → Medellín · about ~1h in the air · ~€45–150
Flight to Guayaquil
Medellín → Guayaquil · about ~1h 35m in the air · ~€60–250
Panama City → Guayaquil
Panama to Ecuador · 2 borders · Where else can you go from Panama City?
Your route
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Scroll for the full route →THE JOURNEY, STEP BY STEP
Your itinerary
About the trip from Panama City to Guayaquil
Panama City (Panama) and Guayaquil (Ecuador) are 1,245 km (774 mi) apart in a straight line. The way we suggest is by flight, via Medellín: ~5h 35m door to door with 1 change, for ~€105–400 per person. The fastest route, by bus and flight via San Miguelito and Tocumen, takes ~5h 15m (~€71–252). The trip crosses 2 borders, so check what papers you need.
Step by step
- Flight from Panama City to Medellín: ~1h in the air, 532 km, ~€45–150
- Flight from Medellín to Guayaquil: ~1h 35m in the air, 1,054 km, ~€60–250
Every route we know
- Flight, via Medellín: ~5h 35m, 1 change, ~€105–400
- Bus + Flight, via San Miguelito and Tocumen: ~5h 15m, 2 changes, ~€71–252
Questions
How long does it take to get from Panama City to Guayaquil?
~5h 35m door to door by flight, via Medellín, including time for changes and airports. The fastest route takes ~5h 15m.
How much does it cost to travel from Panama City to Guayaquil?
~€105–400 per person for the route we suggest. These are estimates from travel-guide prices and published tariffs, not quotes: check the operator for today's fare.
Can you get from Panama City to Guayaquil without flying?
Not in our data: every route we know includes a flight.
Times are rough door-to-door times, with time to change and to get through airports included. A "~" marks a rough time worked out from the distance. We don't have timetables, and fares are rough estimates, not quotes: check Google Maps or the operator before you travel.