Bus to Panama City
Colón → Panama City · about 1h 30m
Flight to Medellín
Panama City → Medellín · about ~1h in the air
Flight to Guayaquil
Medellín → Guayaquil · about ~1h 35m in the air
Colón → Guayaquil
Panama to Ecuador · 2 borders · Where else can you go from Colón?
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Your itinerary
About the trip from Colón to Guayaquil
Colón (Panama) and Guayaquil (Ecuador) are 1,285 km (798 mi) apart in a straight line. The way we suggest is by bus and flight, via Panama City and Medellín: ~8h 5m door to door with 2 changes. The fastest route, by bus and flight via Panama City, San Miguelito and Tocumen, takes ~7h. The trip crosses 2 borders, so check what papers you need.
Step by step
- Bus from Colón to Panama City: about 1h 30m, 58 km
- Flight from Panama City to Medellín: ~1h in the air, 532 km
- Flight from Medellín to Guayaquil: ~1h 35m in the air, 1,054 km
Every route we know
- Bus + Flight, via Panama City and Medellín: ~8h 5m, 2 changes
- Bus + Flight, via Panama City, San Miguelito and Tocumen: ~7h, 3 changes
Times are rough door-to-door times, with time to change and to get through airports included. A "~" marks a rough time worked out from the distance. We don't have prices or timetables: check Google Maps or the operator before you travel.